Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients
Background Rosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis. Aims In this cross‐sectional study, it is aimed to reveal the frequency of...
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Veröffentlicht in: | Journal of cosmetic dermatology 2020-05, Vol.19 (5), p.1260-1265 |
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creator | Sarac, Gulbahar Cankaya, Cem Ozcan, Kubra Nur Cenk, Hülya Kapicioglu, Yelda Karincaoglu |
description | Background
Rosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis.
Aims
In this cross‐sectional study, it is aimed to reveal the frequency of Demodex blepharitis in rosacea and primary demodicosis patients.
Methods
In total, 58 rosacea, 33 primary demodicosis patients, and 31 healthy volunteers were included in the study. Four samples were obtained from eyelashes with a forceps and from facial skin by standardized skin surface biopsy. A positive result is described as detecting at least one Demodex mite on an eyelash or at five mites in the face. The patients were also examined by an ophthalmologist in terms of ocular involvement.
Results
Both rosacea and primary demodicosis patients had significantly more complaints like burning and stinging in the eyes compared to the control patients (P = .001). Primary demodicosis and papulopustular rosacea patients had the highest numbers of eyelash mites, respectively, and significantly a higher rate of blepharitis than the control group.
Conclusion
As a result, the Demodex count was significantly higher in the primary demodicosis and rosacea patients than the control group. We think that every Demodex‐positive patients should be evaluated for also eyelash mites to prevent a possible chronic blepharitis. |
doi_str_mv | 10.1111/jocd.13150 |
format | Article |
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Rosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis.
Aims
In this cross‐sectional study, it is aimed to reveal the frequency of Demodex blepharitis in rosacea and primary demodicosis patients.
Methods
In total, 58 rosacea, 33 primary demodicosis patients, and 31 healthy volunteers were included in the study. Four samples were obtained from eyelashes with a forceps and from facial skin by standardized skin surface biopsy. A positive result is described as detecting at least one Demodex mite on an eyelash or at five mites in the face. The patients were also examined by an ophthalmologist in terms of ocular involvement.
Results
Both rosacea and primary demodicosis patients had significantly more complaints like burning and stinging in the eyes compared to the control patients (P = .001). Primary demodicosis and papulopustular rosacea patients had the highest numbers of eyelash mites, respectively, and significantly a higher rate of blepharitis than the control group.
Conclusion
As a result, the Demodex count was significantly higher in the primary demodicosis and rosacea patients than the control group. We think that every Demodex‐positive patients should be evaluated for also eyelash mites to prevent a possible chronic blepharitis.</description><identifier>ISSN: 1473-2130</identifier><identifier>EISSN: 1473-2165</identifier><identifier>DOI: 10.1111/jocd.13150</identifier><identifier>PMID: 31553138</identifier><language>eng</language><publisher>England</publisher><subject>Adult ; Animals ; Blepharitis - diagnosis ; Blepharitis - epidemiology ; Blepharitis - immunology ; Blepharitis - parasitology ; Case-Control Studies ; chronic blepharitis ; Cross-Sectional Studies ; Demodex ; Demodex blepharitis ; demodicosis ; Eyelashes - parasitology ; Face ; Female ; Humans ; Male ; Middle Aged ; mites ; Mites - immunology ; rosacea ; Rosacea - complications ; Rosacea - immunology</subject><ispartof>Journal of cosmetic dermatology, 2020-05, Vol.19 (5), p.1260-1265</ispartof><rights>2019 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3290-4836b90861341d784a324109238121e23074039d8442b6424dde91676fa6ea0b3</citedby><cites>FETCH-LOGICAL-c3290-4836b90861341d784a324109238121e23074039d8442b6424dde91676fa6ea0b3</cites><orcidid>0000-0003-4871-6342 ; 0000-0002-7246-6382</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjocd.13150$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjocd.13150$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31553138$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sarac, Gulbahar</creatorcontrib><creatorcontrib>Cankaya, Cem</creatorcontrib><creatorcontrib>Ozcan, Kubra Nur</creatorcontrib><creatorcontrib>Cenk, Hülya</creatorcontrib><creatorcontrib>Kapicioglu, Yelda Karincaoglu</creatorcontrib><title>Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients</title><title>Journal of cosmetic dermatology</title><addtitle>J Cosmet Dermatol</addtitle><description>Background
Rosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis.
Aims
In this cross‐sectional study, it is aimed to reveal the frequency of Demodex blepharitis in rosacea and primary demodicosis patients.
Methods
In total, 58 rosacea, 33 primary demodicosis patients, and 31 healthy volunteers were included in the study. Four samples were obtained from eyelashes with a forceps and from facial skin by standardized skin surface biopsy. A positive result is described as detecting at least one Demodex mite on an eyelash or at five mites in the face. The patients were also examined by an ophthalmologist in terms of ocular involvement.
Results
Both rosacea and primary demodicosis patients had significantly more complaints like burning and stinging in the eyes compared to the control patients (P = .001). Primary demodicosis and papulopustular rosacea patients had the highest numbers of eyelash mites, respectively, and significantly a higher rate of blepharitis than the control group.
Conclusion
As a result, the Demodex count was significantly higher in the primary demodicosis and rosacea patients than the control group. We think that every Demodex‐positive patients should be evaluated for also eyelash mites to prevent a possible chronic blepharitis.</description><subject>Adult</subject><subject>Animals</subject><subject>Blepharitis - diagnosis</subject><subject>Blepharitis - epidemiology</subject><subject>Blepharitis - immunology</subject><subject>Blepharitis - parasitology</subject><subject>Case-Control Studies</subject><subject>chronic blepharitis</subject><subject>Cross-Sectional Studies</subject><subject>Demodex</subject><subject>Demodex blepharitis</subject><subject>demodicosis</subject><subject>Eyelashes - parasitology</subject><subject>Face</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>mites</subject><subject>Mites - immunology</subject><subject>rosacea</subject><subject>Rosacea - complications</subject><subject>Rosacea - immunology</subject><issn>1473-2130</issn><issn>1473-2165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90MtKAzEUBuAgiq3VjQ8gsxRhak6SuS2l9VIpdGPXIZOcwZS5mbRo397UqS7N5mTx8XPOT8g10CmEd7_ptJkCh4SekDGIjMcM0uT078_piFx4v6EUsgKSczIKNuHA8zFZL1rtUHk0UeXwY4et3kddFc2x6Qx-RWWN_btydmt9ZNvIdV5pVJFqg1faqjoyB2l154Po1dZiu_WX5KxStcer45yQ9dPj2-wlXq6eF7OHZaw5K2gscp6WBc1T4AJMlgvFmQBaMJ4DA2ScZoLywuRCsDIVTBiDBaRZWqkUFS35hNwOub3rwu5-KxvrNda1arHbeclYkQHLRM4CvRuoDjd4h5XsnW2U20ug8lCjPNQof2oM-OaYuysbNH_0t7cAYACftsb9P1HydTWbD6Hf1HR7RQ</recordid><startdate>202005</startdate><enddate>202005</enddate><creator>Sarac, Gulbahar</creator><creator>Cankaya, Cem</creator><creator>Ozcan, Kubra Nur</creator><creator>Cenk, Hülya</creator><creator>Kapicioglu, Yelda Karincaoglu</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4871-6342</orcidid><orcidid>https://orcid.org/0000-0002-7246-6382</orcidid></search><sort><creationdate>202005</creationdate><title>Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients</title><author>Sarac, Gulbahar ; Cankaya, Cem ; Ozcan, Kubra Nur ; Cenk, Hülya ; Kapicioglu, Yelda Karincaoglu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3290-4836b90861341d784a324109238121e23074039d8442b6424dde91676fa6ea0b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Animals</topic><topic>Blepharitis - diagnosis</topic><topic>Blepharitis - epidemiology</topic><topic>Blepharitis - immunology</topic><topic>Blepharitis - parasitology</topic><topic>Case-Control Studies</topic><topic>chronic blepharitis</topic><topic>Cross-Sectional Studies</topic><topic>Demodex</topic><topic>Demodex blepharitis</topic><topic>demodicosis</topic><topic>Eyelashes - parasitology</topic><topic>Face</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>mites</topic><topic>Mites - immunology</topic><topic>rosacea</topic><topic>Rosacea - complications</topic><topic>Rosacea - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sarac, Gulbahar</creatorcontrib><creatorcontrib>Cankaya, Cem</creatorcontrib><creatorcontrib>Ozcan, Kubra Nur</creatorcontrib><creatorcontrib>Cenk, Hülya</creatorcontrib><creatorcontrib>Kapicioglu, Yelda Karincaoglu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cosmetic dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sarac, Gulbahar</au><au>Cankaya, Cem</au><au>Ozcan, Kubra Nur</au><au>Cenk, Hülya</au><au>Kapicioglu, Yelda Karincaoglu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients</atitle><jtitle>Journal of cosmetic dermatology</jtitle><addtitle>J Cosmet Dermatol</addtitle><date>2020-05</date><risdate>2020</risdate><volume>19</volume><issue>5</issue><spage>1260</spage><epage>1265</epage><pages>1260-1265</pages><issn>1473-2130</issn><eissn>1473-2165</eissn><abstract>Background
Rosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis.
Aims
In this cross‐sectional study, it is aimed to reveal the frequency of Demodex blepharitis in rosacea and primary demodicosis patients.
Methods
In total, 58 rosacea, 33 primary demodicosis patients, and 31 healthy volunteers were included in the study. Four samples were obtained from eyelashes with a forceps and from facial skin by standardized skin surface biopsy. A positive result is described as detecting at least one Demodex mite on an eyelash or at five mites in the face. The patients were also examined by an ophthalmologist in terms of ocular involvement.
Results
Both rosacea and primary demodicosis patients had significantly more complaints like burning and stinging in the eyes compared to the control patients (P = .001). Primary demodicosis and papulopustular rosacea patients had the highest numbers of eyelash mites, respectively, and significantly a higher rate of blepharitis than the control group.
Conclusion
As a result, the Demodex count was significantly higher in the primary demodicosis and rosacea patients than the control group. We think that every Demodex‐positive patients should be evaluated for also eyelash mites to prevent a possible chronic blepharitis.</abstract><cop>England</cop><pmid>31553138</pmid><doi>10.1111/jocd.13150</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-4871-6342</orcidid><orcidid>https://orcid.org/0000-0002-7246-6382</orcidid></addata></record> |
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subjects | Adult Animals Blepharitis - diagnosis Blepharitis - epidemiology Blepharitis - immunology Blepharitis - parasitology Case-Control Studies chronic blepharitis Cross-Sectional Studies Demodex Demodex blepharitis demodicosis Eyelashes - parasitology Face Female Humans Male Middle Aged mites Mites - immunology rosacea Rosacea - complications Rosacea - immunology |
title | Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients |
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