Synthesis and antiproliferative evaluation of novel steroid-benzisoselenazolone hybrids

[Display omitted] •Two novel steroid-benzisoselenazolone hybrids were synthesized.•Hybrids were obtained by condensing of 2-chloroselanylbenzoyl chloride with amino-steroids.•The antiproliferative activity of the hybrids was investigated.•Some hybrids had excellent inhibitory activity on SKOV3 cells...

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Veröffentlicht in:	Steroids 2019-12, Vol.152, p.108502-108502, Article 108502
Hauptverfasser:	Cui, Jianguo, Wei, Meizhen, Pang, Liping, Gan, Chunfang, Xiao, Junan, Shi, Haixin, Zhan, Junyan, Liu, Zhiping, Huang, Yanmin
Format:	Artikel
Sprache:	eng
Schlagworte:	B-norcholesterol Benzisoselenazolone Dehydroepiandrosterone Selenosteroids Steroid-benzisoselenazolone hybrids
Online-Zugang:	Volltext
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