Effect of Ephedrae Herba methanol extract on high-fat diet-induced hyperlipidaemic mice

Context: Ephedrae Herba (EH), the dried stems and leaves of Ephedra sinica Stapf., E. intermedia Schrenk et C. A. Mey., or E. equisetina Bge. (Ephedraceae [Ephedra]) is used to treat respiratory diseases. Recently, especially in the Republic of Korea, EH has also been used for weight reduction. Obje...

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Veröffentlicht in:	Pharmaceutical biology 2019-01, Vol.57 (1), p.676-683
Hauptverfasser:	Lee, Se-Eun, Lim, Chiyeon, Lim, Sehyun, Lee, Byoungho, Cho, Suin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Alanine transaminase Alanine Transaminase - blood Animals Anti-Obesity Agents - pharmacology Body weight Body Weight - drug effects cardiovascular diseases Cholesterol Cholesterol - blood Deoxyribonucleic acid Diet, High-Fat - adverse effects DNA DNA repair Energy metabolism Ephedra sinica Gene expression herbal medicine High fat diet Hyperlipidemia Hyperlipidemias - chemically induced Hyperlipidemias - drug therapy Hyperlipidemias - genetics Lipid peroxidation Lipid Peroxidation - drug effects Liver Liver - drug effects Male Malondialdehyde Metabolism Methanol Mice Mice, Inbred ICR Obesity Oral administration Plant Extracts - chemistry Plant Extracts - pharmacology Protein turnover Proteins Respiratory diseases Toxicity Triglycerides Triglycerides - blood weight reduction
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