Prognostic factors for survival of herpes simplex virus-associated hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) occurs in neonates with disseminated infection of herpes simplex virus (HSV). Little has been reported on the control of rapid HLH progression. We studied the cytokine profile and genetic basis of two index cases with divergent outcomes after early treatment...

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Veröffentlicht in:	International journal of hematology 2020-01, Vol.111 (1), p.131-136
Hauptverfasser:	Sonoda, Motoshi, Ishimura, Masataka, Eguchi, Katsuhide, Shiraishi, Akira, Kanno, Shunsuke, Kaku, Noriyuki, Inoue, Hirosuke, Motomura, Yoshitomo, Ochiai, Masayuki, Sakai, Yasunari, Nakayama, Manabu, Ohara, Osamu, Ohga, Shouichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytokines Diagnosis Disseminated infection Ferritin Fever Hematology Herpes simplex Herpes viruses Histiocytosis Infections Interferon Interleukin 2 Interleukin 2 receptors Interleukin 6 Interleukins Lymphatic diseases Lymphocytosis Medical prognosis Medicine Medicine & Public Health Neonates Newborn babies Oncology Original Article Platelets Serum levels Survival Tumor necrosis factor-TNF Tumor necrosis factor-α Viruses γ-Interferon
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