A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study

Purpose Laparoendoscopic single-site donor nephrectomy (LESSDN) is a feasible and effective procedure because of its non-invasiveness and better cosmetic outcomes. However, there have been few multi-institutional studies conducted by multiple surgeons on LESSDN. We retrospectively compared the clini...

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Veröffentlicht in:Surgical endoscopy 2020-08, Vol.34 (8), p.3424-3434
Hauptverfasser: Inoue, Takamitsu, Miura, Masayoshi, Yanishi, Masaaki, Furukawa, Junya, Sato, Fuminori, Nitta, Masahiro, Yoshimura, Koji, Hagiuda, Jun, Shinoda, Kazunobu, Kobayashi, Takashi, Miyajima, Akira, Nakagawa, Ken, Oya, Mototsugu, Ogawa, Osamu, Mimata, Hiromitsu, Kanayama, Hiro-omi, Fujisawa, Masato, Terachi, Toshiro, Matsuda, Tadashi, Habuchi, Tomonori
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container_end_page 3434
container_issue 8
container_start_page 3424
container_title Surgical endoscopy
container_volume 34
creator Inoue, Takamitsu
Miura, Masayoshi
Yanishi, Masaaki
Furukawa, Junya
Sato, Fuminori
Nitta, Masahiro
Yoshimura, Koji
Hagiuda, Jun
Shinoda, Kazunobu
Kobayashi, Takashi
Miyajima, Akira
Nakagawa, Ken
Oya, Mototsugu
Ogawa, Osamu
Mimata, Hiromitsu
Kanayama, Hiro-omi
Fujisawa, Masato
Terachi, Toshiro
Matsuda, Tadashi
Habuchi, Tomonori
description Purpose Laparoendoscopic single-site donor nephrectomy (LESSDN) is a feasible and effective procedure because of its non-invasiveness and better cosmetic outcomes. However, there have been few multi-institutional studies conducted by multiple surgeons on LESSDN. We retrospectively compared the clinical data and outcomes between LESSDN and conventional laparoscopic donor nephrectomy (LDN) at multiple institutes in Japan. Materials and methods From 2009 to 2015, the clinical data of 223 donors who underwent LESSDN and 151 donors who underwent LDN were collected from 10 institutes. All LESSDNs were performed transperitoneally, whereas LDNs were performed transperitoneally (P-LDN) in 75 patients and retroperitoneally (R-LDN) in 76 patients. Results In the LESSDN group, the single-incision site was pararectal in 155 (69.5%) patients and umbilical in 65 (29.1%) patients. Multiple surgeons (one to eight per institute) performed the LESSDN. No significant differences were observed between the three groups regarding estimated blood loss and warm ischemic time. The operative time was significantly shorter in the LESSDN group than in the R-LDN group ( p  = 0.018). No significant differences were observed regarding the rates of blood transfusion, open conversion, visceral injuries, and postoperative complications. Furthermore, no significant differences were observed regarding the dose of analgesic and the rate of delayed graft function. One patient required open conversion due to injury to the renal artery. Selection of LESS procedure was not an independent risk factor for the median serum creatinine level of above 1.27 mg/dL in recipients at 1 year after kidney transplantation. Conclusion The results showed the technical feasibility of LESSDN compared with the standard LDNs in a multi-institutional and multi-surgeon setting. A few observed non-negligible complications and the significantly higher levels of serum creatinine in patients who underwent LESSDN indicate that this procedure should be employed cautiously when performed by surgeons without ample experience in performing LESS procedures.
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However, there have been few multi-institutional studies conducted by multiple surgeons on LESSDN. We retrospectively compared the clinical data and outcomes between LESSDN and conventional laparoscopic donor nephrectomy (LDN) at multiple institutes in Japan. Materials and methods From 2009 to 2015, the clinical data of 223 donors who underwent LESSDN and 151 donors who underwent LDN were collected from 10 institutes. All LESSDNs were performed transperitoneally, whereas LDNs were performed transperitoneally (P-LDN) in 75 patients and retroperitoneally (R-LDN) in 76 patients. Results In the LESSDN group, the single-incision site was pararectal in 155 (69.5%) patients and umbilical in 65 (29.1%) patients. Multiple surgeons (one to eight per institute) performed the LESSDN. No significant differences were observed between the three groups regarding estimated blood loss and warm ischemic time. The operative time was significantly shorter in the LESSDN group than in the R-LDN group ( p  = 0.018). No significant differences were observed regarding the rates of blood transfusion, open conversion, visceral injuries, and postoperative complications. Furthermore, no significant differences were observed regarding the dose of analgesic and the rate of delayed graft function. One patient required open conversion due to injury to the renal artery. Selection of LESS procedure was not an independent risk factor for the median serum creatinine level of above 1.27 mg/dL in recipients at 1 year after kidney transplantation. Conclusion The results showed the technical feasibility of LESSDN compared with the standard LDNs in a multi-institutional and multi-surgeon setting. A few observed non-negligible complications and the significantly higher levels of serum creatinine in patients who underwent LESSDN indicate that this procedure should be employed cautiously when performed by surgeons without ample experience in performing LESS procedures.</description><identifier>ISSN: 0930-2794</identifier><identifier>EISSN: 1432-2218</identifier><identifier>DOI: 10.1007/s00464-019-07119-9</identifier><identifier>PMID: 31549237</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Abdominal Surgery ; Endoscopy ; Gastroenterology ; Gynecology ; Hepatology ; Hospitals ; Kidney transplants ; Laparoscopy ; Medicine ; Medicine &amp; Public Health ; Patient satisfaction ; Proctology ; Surgeons ; Surgery ; Transplants &amp; implants ; University graduates ; Urology</subject><ispartof>Surgical endoscopy, 2020-08, Vol.34 (8), p.3424-3434</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-63f9358063ec14e9ac276ac41c45354f5abb7d7c401a079d82507774f3abaf213</citedby><cites>FETCH-LOGICAL-c441t-63f9358063ec14e9ac276ac41c45354f5abb7d7c401a079d82507774f3abaf213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00464-019-07119-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00464-019-07119-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31549237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Inoue, Takamitsu</creatorcontrib><creatorcontrib>Miura, Masayoshi</creatorcontrib><creatorcontrib>Yanishi, Masaaki</creatorcontrib><creatorcontrib>Furukawa, Junya</creatorcontrib><creatorcontrib>Sato, Fuminori</creatorcontrib><creatorcontrib>Nitta, Masahiro</creatorcontrib><creatorcontrib>Yoshimura, Koji</creatorcontrib><creatorcontrib>Hagiuda, Jun</creatorcontrib><creatorcontrib>Shinoda, Kazunobu</creatorcontrib><creatorcontrib>Kobayashi, Takashi</creatorcontrib><creatorcontrib>Miyajima, Akira</creatorcontrib><creatorcontrib>Nakagawa, Ken</creatorcontrib><creatorcontrib>Oya, Mototsugu</creatorcontrib><creatorcontrib>Ogawa, Osamu</creatorcontrib><creatorcontrib>Mimata, Hiromitsu</creatorcontrib><creatorcontrib>Kanayama, Hiro-omi</creatorcontrib><creatorcontrib>Fujisawa, Masato</creatorcontrib><creatorcontrib>Terachi, Toshiro</creatorcontrib><creatorcontrib>Matsuda, Tadashi</creatorcontrib><creatorcontrib>Habuchi, Tomonori</creatorcontrib><creatorcontrib>LESS and RPS Research Group in Japanese Society of Endourology</creatorcontrib><creatorcontrib>LESS and RPS Research Group in Japanese Society of Endourology</creatorcontrib><title>A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study</title><title>Surgical endoscopy</title><addtitle>Surg Endosc</addtitle><addtitle>Surg Endosc</addtitle><description>Purpose Laparoendoscopic single-site donor nephrectomy (LESSDN) is a feasible and effective procedure because of its non-invasiveness and better cosmetic outcomes. However, there have been few multi-institutional studies conducted by multiple surgeons on LESSDN. We retrospectively compared the clinical data and outcomes between LESSDN and conventional laparoscopic donor nephrectomy (LDN) at multiple institutes in Japan. Materials and methods From 2009 to 2015, the clinical data of 223 donors who underwent LESSDN and 151 donors who underwent LDN were collected from 10 institutes. All LESSDNs were performed transperitoneally, whereas LDNs were performed transperitoneally (P-LDN) in 75 patients and retroperitoneally (R-LDN) in 76 patients. Results In the LESSDN group, the single-incision site was pararectal in 155 (69.5%) patients and umbilical in 65 (29.1%) patients. Multiple surgeons (one to eight per institute) performed the LESSDN. No significant differences were observed between the three groups regarding estimated blood loss and warm ischemic time. The operative time was significantly shorter in the LESSDN group than in the R-LDN group ( p  = 0.018). No significant differences were observed regarding the rates of blood transfusion, open conversion, visceral injuries, and postoperative complications. Furthermore, no significant differences were observed regarding the dose of analgesic and the rate of delayed graft function. One patient required open conversion due to injury to the renal artery. Selection of LESS procedure was not an independent risk factor for the median serum creatinine level of above 1.27 mg/dL in recipients at 1 year after kidney transplantation. Conclusion The results showed the technical feasibility of LESSDN compared with the standard LDNs in a multi-institutional and multi-surgeon setting. A few observed non-negligible complications and the significantly higher levels of serum creatinine in patients who underwent LESSDN indicate that this procedure should be employed cautiously when performed by surgeons without ample experience in performing LESS procedures.</description><subject>Abdominal Surgery</subject><subject>Endoscopy</subject><subject>Gastroenterology</subject><subject>Gynecology</subject><subject>Hepatology</subject><subject>Hospitals</subject><subject>Kidney transplants</subject><subject>Laparoscopy</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Patient satisfaction</subject><subject>Proctology</subject><subject>Surgeons</subject><subject>Surgery</subject><subject>Transplants &amp; implants</subject><subject>University graduates</subject><subject>Urology</subject><issn>0930-2794</issn><issn>1432-2218</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kc1u1DAUhS1ERYfCC7BAltiwCfgv8ZhdVRXaqlI3sI48zk1xldjBPyPNK_UpuXQCSCzY2LL9nXPv9SHkDWcfOGP6Y2ZMdaph3DRMc1zNM7LhSopGCL59TjbMSNYIbdQpeZnzA0Pe8PYFOZW8VUZIvSGP59TFebHJ5xhoHOlk8RAhDDG7uHhHsw_3EzTZF6C5pntIB7qHlGtGZdhDKD4GO9ElRQdDTZDpGNPqs3oMMeBVgOV7AlfifPhELb1BIkAGOtep-MaHXHypq1uCguoFab_HuqUOh1fkZLRThtfrfka-fb78enHV3N59ub44v22cUrw0nRyNbLesk-C4AmOd0J11ijvVylaNrd3t9KCdYtwybYataJnWWo3S7uwouDwj74--ONGPCrn0s88Opgm7jTX3Qpiua_EDO0Tf_YM-xJqw_yeq3UrsQiMljpTDkXKCsV-Sn2069Jz1v5Lsj0n2mGT_lGRvUPR2ta67GYY_kt_RISCPQMangLH8rf0f258nGK5J</recordid><startdate>20200801</startdate><enddate>20200801</enddate><creator>Inoue, Takamitsu</creator><creator>Miura, Masayoshi</creator><creator>Yanishi, Masaaki</creator><creator>Furukawa, Junya</creator><creator>Sato, Fuminori</creator><creator>Nitta, Masahiro</creator><creator>Yoshimura, Koji</creator><creator>Hagiuda, Jun</creator><creator>Shinoda, Kazunobu</creator><creator>Kobayashi, Takashi</creator><creator>Miyajima, Akira</creator><creator>Nakagawa, Ken</creator><creator>Oya, Mototsugu</creator><creator>Ogawa, Osamu</creator><creator>Mimata, Hiromitsu</creator><creator>Kanayama, Hiro-omi</creator><creator>Fujisawa, Masato</creator><creator>Terachi, Toshiro</creator><creator>Matsuda, Tadashi</creator><creator>Habuchi, Tomonori</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20200801</creationdate><title>A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study</title><author>Inoue, Takamitsu ; 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Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Surgical endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inoue, Takamitsu</au><au>Miura, Masayoshi</au><au>Yanishi, Masaaki</au><au>Furukawa, Junya</au><au>Sato, Fuminori</au><au>Nitta, Masahiro</au><au>Yoshimura, Koji</au><au>Hagiuda, Jun</au><au>Shinoda, Kazunobu</au><au>Kobayashi, Takashi</au><au>Miyajima, Akira</au><au>Nakagawa, Ken</au><au>Oya, Mototsugu</au><au>Ogawa, Osamu</au><au>Mimata, Hiromitsu</au><au>Kanayama, Hiro-omi</au><au>Fujisawa, Masato</au><au>Terachi, Toshiro</au><au>Matsuda, Tadashi</au><au>Habuchi, Tomonori</au><aucorp>LESS and RPS Research Group in Japanese Society of Endourology</aucorp><aucorp>LESS and RPS Research Group in Japanese Society of Endourology</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study</atitle><jtitle>Surgical endoscopy</jtitle><stitle>Surg Endosc</stitle><addtitle>Surg Endosc</addtitle><date>2020-08-01</date><risdate>2020</risdate><volume>34</volume><issue>8</issue><spage>3424</spage><epage>3434</epage><pages>3424-3434</pages><issn>0930-2794</issn><eissn>1432-2218</eissn><abstract>Purpose Laparoendoscopic single-site donor nephrectomy (LESSDN) is a feasible and effective procedure because of its non-invasiveness and better cosmetic outcomes. However, there have been few multi-institutional studies conducted by multiple surgeons on LESSDN. We retrospectively compared the clinical data and outcomes between LESSDN and conventional laparoscopic donor nephrectomy (LDN) at multiple institutes in Japan. Materials and methods From 2009 to 2015, the clinical data of 223 donors who underwent LESSDN and 151 donors who underwent LDN were collected from 10 institutes. All LESSDNs were performed transperitoneally, whereas LDNs were performed transperitoneally (P-LDN) in 75 patients and retroperitoneally (R-LDN) in 76 patients. Results In the LESSDN group, the single-incision site was pararectal in 155 (69.5%) patients and umbilical in 65 (29.1%) patients. Multiple surgeons (one to eight per institute) performed the LESSDN. No significant differences were observed between the three groups regarding estimated blood loss and warm ischemic time. The operative time was significantly shorter in the LESSDN group than in the R-LDN group ( p  = 0.018). No significant differences were observed regarding the rates of blood transfusion, open conversion, visceral injuries, and postoperative complications. Furthermore, no significant differences were observed regarding the dose of analgesic and the rate of delayed graft function. One patient required open conversion due to injury to the renal artery. Selection of LESS procedure was not an independent risk factor for the median serum creatinine level of above 1.27 mg/dL in recipients at 1 year after kidney transplantation. Conclusion The results showed the technical feasibility of LESSDN compared with the standard LDNs in a multi-institutional and multi-surgeon setting. A few observed non-negligible complications and the significantly higher levels of serum creatinine in patients who underwent LESSDN indicate that this procedure should be employed cautiously when performed by surgeons without ample experience in performing LESS procedures.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>31549237</pmid><doi>10.1007/s00464-019-07119-9</doi><tpages>11</tpages></addata></record>
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subjects Abdominal Surgery
Endoscopy
Gastroenterology
Gynecology
Hepatology
Hospitals
Kidney transplants
Laparoscopy
Medicine
Medicine & Public Health
Patient satisfaction
Proctology
Surgeons
Surgery
Transplants & implants
University graduates
Urology
title A comparison of laparoendoscopic single-site surgery versus conventional procedures for laparoscopic donor nephrectomy: a Japanese multi-institutional retrospective study
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