Sex differences in depressive-like behaviour may relate to imbalance of microglia activation in the hippocampus

•Female mice are more sensitive to CUMS.•CUMS activates microglia in both sex mice differently.•BDNF contributes differently to the sex differences in depression.•Microglia-neuroinflammation-BDNF may be a potential mechanism for sex differences in depression. As is reported, the incidence and preval...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2019-10, Vol.81, p.188-197
Hauptverfasser:	Liu, Lin-Lin, Li, Jia-Mei, Su, Wen-Jun, Wang, Bo, Jiang, Chun-Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	BDNF Depression Hippocampus Inflammation Microglia Sex difference
Online-Zugang:	Volltext
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