Successful treatment of co‐existent SAPHO syndrome and hidradenitis suppurativa with adalimumab and methotrexate
SAPHO syndrome, namely Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis, is a rare autoinflammatory chronic disease presenting with non‐infectious inflammatory osteitis, sterile joint inflammation and skin manifestations, including palmoplantar pustulosis and severe acne. The case of a 15‐year...
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| Veröffentlicht in: | Journal of the European Academy of Dermatology and Venereology 2019-10, Vol.33 (S6), p.40-41 |
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| container_issue | S6 |
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| container_title | Journal of the European Academy of Dermatology and Venereology |
| container_volume | 33 |
| creator | Genovese, G. Caorsi, R. Moltrasio, C. Marzano, A.V. |
| description | SAPHO syndrome, namely Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis, is a rare autoinflammatory chronic disease presenting with non‐infectious inflammatory osteitis, sterile joint inflammation and skin manifestations, including palmoplantar pustulosis and severe acne. The case of a 15‐year‐old boy affected by SAPHO syndrome and hidradenitis suppurativa (HS) is presented and discussed. Coexistence of these two diseases may represent a therapeutic challenge and this case confirms literature data reporting the efficacy of the combination of methotrexate and adalimumab in SAPHO complicated by HS. |
| doi_str_mv | 10.1111/jdv.15849 |
| format | Article |
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The case of a 15‐year‐old boy affected by SAPHO syndrome and hidradenitis suppurativa (HS) is presented and discussed. 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The case of a 15‐year‐old boy affected by SAPHO syndrome and hidradenitis suppurativa (HS) is presented and discussed. 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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Acquired Hyperostosis Syndrome - complications Acquired Hyperostosis Syndrome - drug therapy Adalimumab - therapeutic use Adolescent Anti-Inflammatory Agents - therapeutic use Dermatologic Agents - therapeutic use Hidradenitis Suppurativa - complications Hidradenitis Suppurativa - drug therapy Humans Male Methotrexate - therapeutic use Prednisone - therapeutic use |
| title | Successful treatment of co‐existent SAPHO syndrome and hidradenitis suppurativa with adalimumab and methotrexate |
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