Dissecting the mechanisms of bone loss in Gorham-Stout disease

•Bone biopsy analysis of Gorham-Stout patients revealed increased vessels, osteoclast number and osteocyte lacunar area.•In vitro experiments displayed increased osteoclast differentiation/activity and reduced osteoblast function.•Patients’ sera stimulated osteoclastogenesis, bone resorption and red...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2020-01, Vol.130, p.115068-115068, Article 115068
Hauptverfasser:	Rossi, Michela, Buonuomo, Paola Sabrina, Battafarano, Giulia, Conforti, Antonella, Mariani, Eda, Algeri, Mattia, Pelle, Simone, D’Agostini, Matteo, Macchiaiolo, Marina, De Vito, Rita, Gonfiantini, Michaela Veronika, Jenkner, Alessandro, Rana, Ippolita, Bartuli, Andrea, Del Fattore, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone and Bones Bone histomorphometry Endothelial Cells Gorham-Stout disease Humans Osteoblast Osteoclast Osteoclasts Osteolysis Osteolysis, Essential
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!