Involvement of neural substrates in reward and aversion to methamphetamine addiction: Testing the reward comparison hypothesis and the paradoxical effect hypothesis of abused drugs

•The Cg1, IL, PrL, BLA, NAc, and DG probably mediated the paradoxical effect—reward and aversion.•Rewarding and aversive neural substrates involve in methamphetamine’s conditioned suppression.•Our data conflict the reward comparison but support the paradoxical effect hypothesis of abused drugs.•The...

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Veröffentlicht in:	Neurobiology of learning and memory 2019-12, Vol.166, p.107090-107090, Article 107090
Hauptverfasser:	He, Alan Bo Han, Huang, Chung Lei, Kozłowska, Anna, Chen, Jun Chien, Wu, Chi-Wen, Huang, Andrew Chih Wei, Liu, Yu Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aversion c-Fos Methamphetamine Neural substrates p-ERK Reward
Online-Zugang:	Volltext
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