Insight into the distribution of amino groups along the chain of chemically deacetylated hyaluronan

•Methodology to describe distribution of deacetylation along HA chain was developed.•Deacetylation pattern was independent on Mw of HA and reaction conditions.•Deacetylation pattern did not agree with random distribution model.•Probability of deacetylation at the closest neighboring disaccharide was...

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Veröffentlicht in:	Carbohydrate polymers 2019-12, Vol.225, p.115156-115156, Article 115156
Hauptverfasser:	Sedláček, Jakub, Hermannová, Martina, Mrázek, Jiří, Buffa, Radovan, Lišková, Petra, Šatínský, Dalibor, Velebný, Vladimír
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Acetylglucosamine - chemistry Deacetylation Distribution of modification Hyaluronan Hyaluronic Acid - chemistry Nitrous Acid - chemistry Polysaccharide-Lyases - chemistry Streptococcus pneumoniae - enzymology
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