Tenofovir disoproxil fumarate reduces hepatocellular carcinoma, decompensation and death in chronic hepatitis B patients with cirrhosis

Summary Background Lamivudine and entecavir reduce hepatic events and death in chronic hepatitis B (CHB) patients with cirrhosis, but the impact of tenofovir disoproxil fumarate (TDF) is less well studied. Aim To investigate the effectiveness of TDF therapy in CHB patients with cirrhosis. Methods We...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2019-11, Vol.50 (9), p.1037-1048
Hauptverfasser:	Liu, Ken, Choi, Jonggi, Le, An, Yip, Terry Cheuk‐Fung, Wong, Vincent Wai‐Sun, Chan, Stephen Lam, Chan, Henry Lik‐Yuen, Nguyen, Mindie H., Lim, Young‐Suk, Wong, Grace Lai‐Hung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - therapeutic use Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - prevention & control Cirrhosis Cohort Studies Death Female Hepatitis Hepatitis B Hepatitis B, Chronic - complications Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - mortality Hepatitis B, Chronic - pathology Hepatocellular carcinoma Humans Lamivudine Liver Liver cancer Liver cirrhosis Liver Cirrhosis - complications Liver Cirrhosis - drug therapy Liver Cirrhosis - mortality Liver diseases Liver Failure - etiology Liver Failure - mortality Liver Failure - pathology Liver Failure - prevention & control Liver Neoplasms - mortality Liver Neoplasms - pathology Liver Neoplasms - prevention & control Liver transplantation Liver Transplantation - statistics & numerical data Male Medical treatment Middle Aged Patients Retrospective Studies Survival Analysis Tenofovir Tenofovir - therapeutic use Transplantation Treatment Outcome
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