LINC01210 accelerates proliferation, invasion and migration in ovarian cancer through epigenetically downregulating KLF4

•This is the first time to demonstrate that LINC01210 was up-regulated in OC.•The up-regulated LINC01210 promoted OC proliferation, invasion and migration.•LINC01210 accelerates OC progression through epigenetically downregulating KLF4. In recent years, a large number of studies have shown that diff...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2019-11, Vol.119, p.109431-109431, Article 109431
Hauptverfasser:	Zhang, Chu, Liu, Jie, Zhang, Yang, Luo, Chengyan, Zhu, Tong, Zhang, Rongrong, Yao, Ruiqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Down-Regulation - genetics Enhancer of Zeste Homolog 2 Protein - metabolism Epigenesis, Genetic Female Gene Expression Regulation, Neoplastic Gene Silencing Humans Invasion KLF4 Kruppel-Like Transcription Factors - genetics Kruppel-Like Transcription Factors - metabolism LINC01210 Migration Models, Biological Neoplasm Invasiveness Neoplasm Metastasis Oncogenes Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Prognosis Proliferation Protein Binding RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Up-Regulation - genetics
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