Modulation of foreign body reaction and macrophage phenotypes concerning microenvironment

The foreign body reaction (FBR) is described as a local chronic inflammation after implantation of biomaterials in which macrophages involved intimately. At the stage of acute inflammation, mast cells release histamine, Interleukin‐4 (IL‐4) and Interleukin‐13 (IL‐13), enhancing recruitment, and fusi...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2020-01, Vol.108 (1), p.127-135
Hauptverfasser:	Chu, Chenyu, Liu, Li, Rung, Shengan, Wang, Yuanjing, Ma, Yuxing, Hu, Chen, Zhao, Xiwen, Man, Yi, Qu, Yili
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomaterials Biomedical materials Cytokines foreign body reaction Giant cells Histamine Immune response Implantation Inflammation Interleukins Intermediates Macrophages Mast cells Phenotypes Reactive oxygen species Surgical implants
Online-Zugang:	Volltext
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