GJB2‐related hearing loss in central Iran: Review of the spectrum and frequency of gene mutations

Mutations in the GJB2 gene are a main cause of autosomal‐recessive nonsyndromic hearing loss (ARNSHL) in many populations. Previous studies have estimated the average frequency of GJB2 mutations to be ∼16% in Iran, but would vary among different ethnic groups. Here, we have taken together and review...

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Veröffentlicht in:	Annals of human genetics 2020-03, Vol.84 (2), p.107-113
Hauptverfasser:	Koohiyan, Mahbobeh, Koohian, Farideh, Azadegan‐Dehkordi, Fatemeh
Format:	Artikel
Sprache:	eng
Schlagworte:	clinical guidelines Connexins - genetics Genetic counseling GJB2 GJB2 protein Hearing loss Hearing Loss - genetics Hearing Loss - pathology Humans Iranian population Minority & ethnic groups Mutation Mutation Rate nonsyndromic hearing loss Population studies
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