Equid Herpesvirus 1 Targets the Sensitization and Induction Steps To Inhibit the Type I Interferon Response in Equine Endothelial Cells

Equid herpesvirus 1 (EHV-1) is a viral pathogen of horse populations worldwide spread by the respiratory route and is known for causing outbreaks of neurologic syndromes and abortion storms. Previously, we demonstrated that an EHV-1 strain of the neuropathogenic genotype, T953, downregulates the bet...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of virology 2019-12, Vol.93 (23)
Hauptverfasser:	Oladunni, Fatai S, Sarkar, Sanjay, Reedy, Stephanie, Balasuriya, Udeni B R, Horohov, David W, Chambers, Thomas M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endothelial Cells - metabolism Endothelial Cells - virology Gene Expression Regulation Hepatitis B, Chronic Herpesviridae Infections - immunology Herpesviridae Infections - metabolism Herpesviridae Infections - virology Herpesvirus 1, Equid - genetics Herpesvirus 1, Equid - immunology Horse Diseases - virology Horses Host-Pathogen Interactions Humans Immunity, Innate Interferon Type I - metabolism Janus Kinase 1 - metabolism RNA, Messenger - metabolism Signal Transduction STAT2 Transcription Factor - metabolism Toll-Like Receptor 3 - metabolism Toll-Like Receptor 4 - metabolism TYK2 Kinase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!