Acute Encephalitis Syndrome with an Unusual Diagnosis
Abstract Four-year old boy was admitted with acute onset of fever with seizures and altered sensorium. His mother had history of contact with influenza A H1N1 virus (H1N1) infection. Blood counts, electrolytes, blood sugar and ammonia were normal. Liver enzymes were mildly elevated. CSF study showed...
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Veröffentlicht in: | Journal of tropical pediatrics (1980) 2020-04, Vol.66 (2), p.228-230 |
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creator | Thomas, Mili Swarnam, Kamala Remadevi, Gopika Sekhar Pillai, A Marthanda |
description | Abstract
Four-year old boy was admitted with acute onset of fever with seizures and altered sensorium. His mother had history of contact with influenza A H1N1 virus (H1N1) infection. Blood counts, electrolytes, blood sugar and ammonia were normal. Liver enzymes were mildly elevated. CSF study showed elevated protein, normal sugar and no pleocytosis. Cerebrospinal fluid (CSF) viral panel was negative. Magnetic resonance imaging brain was suggestive of acute necrotizing encephalopathy. His throat swab and sputum polymerase chain reaction was positive for H1N1. He was managed with ventilation, intravenous steroids and other supportive measures. At discharge his sensorium improved but had neurological sequelae. We are presenting this case as this is a very rare complication of H1N1 infection with high rate of mortality. Early supportive measures and steroids/intravenous immunoglobulin may save the patient. |
doi_str_mv | 10.1093/tropej/fmz058 |
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Four-year old boy was admitted with acute onset of fever with seizures and altered sensorium. His mother had history of contact with influenza A H1N1 virus (H1N1) infection. Blood counts, electrolytes, blood sugar and ammonia were normal. Liver enzymes were mildly elevated. CSF study showed elevated protein, normal sugar and no pleocytosis. Cerebrospinal fluid (CSF) viral panel was negative. Magnetic resonance imaging brain was suggestive of acute necrotizing encephalopathy. His throat swab and sputum polymerase chain reaction was positive for H1N1. He was managed with ventilation, intravenous steroids and other supportive measures. At discharge his sensorium improved but had neurological sequelae. We are presenting this case as this is a very rare complication of H1N1 infection with high rate of mortality. Early supportive measures and steroids/intravenous immunoglobulin may save the patient.</description><identifier>ISSN: 0142-6338</identifier><identifier>EISSN: 1465-3664</identifier><identifier>DOI: 10.1093/tropej/fmz058</identifier><identifier>PMID: 31504992</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><ispartof>Journal of tropical pediatrics (1980), 2020-04, Vol.66 (2), p.228-230</ispartof><rights>The Author(s) [2019]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com 2019</rights><rights>The Author(s) [2019]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-c7905706b908f0b675bf1834d3cd6769c410a83d08a4d8ec1f37370156c5ee2f3</citedby><cites>FETCH-LOGICAL-c365t-c7905706b908f0b675bf1834d3cd6769c410a83d08a4d8ec1f37370156c5ee2f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31504992$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thomas, Mili</creatorcontrib><creatorcontrib>Swarnam, Kamala</creatorcontrib><creatorcontrib>Remadevi, Gopika Sekhar</creatorcontrib><creatorcontrib>Pillai, A Marthanda</creatorcontrib><title>Acute Encephalitis Syndrome with an Unusual Diagnosis</title><title>Journal of tropical pediatrics (1980)</title><addtitle>J Trop Pediatr</addtitle><description>Abstract
Four-year old boy was admitted with acute onset of fever with seizures and altered sensorium. His mother had history of contact with influenza A H1N1 virus (H1N1) infection. Blood counts, electrolytes, blood sugar and ammonia were normal. Liver enzymes were mildly elevated. CSF study showed elevated protein, normal sugar and no pleocytosis. Cerebrospinal fluid (CSF) viral panel was negative. Magnetic resonance imaging brain was suggestive of acute necrotizing encephalopathy. His throat swab and sputum polymerase chain reaction was positive for H1N1. He was managed with ventilation, intravenous steroids and other supportive measures. At discharge his sensorium improved but had neurological sequelae. We are presenting this case as this is a very rare complication of H1N1 infection with high rate of mortality. Early supportive measures and steroids/intravenous immunoglobulin may save the patient.</description><issn>0142-6338</issn><issn>1465-3664</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNqFkDtPwzAYRS0EoqUwsqKMLKGf385YlfKQkBigc-Q4NnWVF3EsVH49RSkwMt3l6FzpIHSJ4QZDRudD33Z2O3f1J3B1hKaYCZ5SIdgxmgJmJBWUqgk6C2ELAEQxdoomFHNgWUamiC9MHGyyaoztNrrygw_Jy64p-7a2yYcfNoluknUTQ9RVcuv1W9MGH87RidNVsBeHnaH13ep1-ZA-Pd8_LhdPqaGCD6mRGXAJoshAOSiE5IXDirKSmlJIkRmGQStagtKsVNZgRyWVgLkw3Fri6Axdj96ub9-jDUNe-2BsVenGtjHkhCglOSEY79F0RE3fhtBbl3e9r3W_yzHk36XysVQ-ltrzVwd1LGpb_tI_af6-29j94_oC0pJzKw</recordid><startdate>20200401</startdate><enddate>20200401</enddate><creator>Thomas, Mili</creator><creator>Swarnam, Kamala</creator><creator>Remadevi, Gopika Sekhar</creator><creator>Pillai, A Marthanda</creator><general>Oxford University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20200401</creationdate><title>Acute Encephalitis Syndrome with an Unusual Diagnosis</title><author>Thomas, Mili ; Swarnam, Kamala ; Remadevi, Gopika Sekhar ; Pillai, A Marthanda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-c7905706b908f0b675bf1834d3cd6769c410a83d08a4d8ec1f37370156c5ee2f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thomas, Mili</creatorcontrib><creatorcontrib>Swarnam, Kamala</creatorcontrib><creatorcontrib>Remadevi, Gopika Sekhar</creatorcontrib><creatorcontrib>Pillai, A Marthanda</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of tropical pediatrics (1980)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thomas, Mili</au><au>Swarnam, Kamala</au><au>Remadevi, Gopika Sekhar</au><au>Pillai, A Marthanda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute Encephalitis Syndrome with an Unusual Diagnosis</atitle><jtitle>Journal of tropical pediatrics (1980)</jtitle><addtitle>J Trop Pediatr</addtitle><date>2020-04-01</date><risdate>2020</risdate><volume>66</volume><issue>2</issue><spage>228</spage><epage>230</epage><pages>228-230</pages><issn>0142-6338</issn><eissn>1465-3664</eissn><abstract>Abstract
Four-year old boy was admitted with acute onset of fever with seizures and altered sensorium. His mother had history of contact with influenza A H1N1 virus (H1N1) infection. Blood counts, electrolytes, blood sugar and ammonia were normal. Liver enzymes were mildly elevated. CSF study showed elevated protein, normal sugar and no pleocytosis. Cerebrospinal fluid (CSF) viral panel was negative. Magnetic resonance imaging brain was suggestive of acute necrotizing encephalopathy. His throat swab and sputum polymerase chain reaction was positive for H1N1. He was managed with ventilation, intravenous steroids and other supportive measures. At discharge his sensorium improved but had neurological sequelae. We are presenting this case as this is a very rare complication of H1N1 infection with high rate of mortality. Early supportive measures and steroids/intravenous immunoglobulin may save the patient.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>31504992</pmid><doi>10.1093/tropej/fmz058</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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title | Acute Encephalitis Syndrome with an Unusual Diagnosis |
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