Immunogenicity of High Dose Influenza Vaccine for Patients with Inflammatory Bowel Disease on Anti-TNF Monotherapy: A Randomized Clinical Trial

BackgroundPatients with inflammatory bowel disease (IBD) on anti-tumor necrosis factor alpha (TNF) agents may have lower immune response to the influenza vaccine. We aimed to evaluate the immunogenicity of the high dose (HD) vs standard dose (SD) influenza vaccine in patients with IBD on anti-TNF mo...

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Veröffentlicht in:	Inflammatory bowel diseases 2020-03, Vol.26 (4), p.593-602
Hauptverfasser:	Caldera, Freddy, Hillman, Luke, Saha, Sumona, Wald, Arnold, Grimes, Ian, Zhang, Youqi, Sharpe, Abigail R, Reichelderfer, Mark, Hayney, Mary S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adalimumab Adult Antibodies, Monoclonal, Humanized Antibodies, Viral - blood Clinical trials Female Gastrointestinal diseases Hemagglutination Inhibition Tests High-definition television Humans Immune response Immunogenicity, Vaccine Immunosuppressive agents Inflammatory Bowel Diseases - drug therapy Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - virology Influenza Influenza A Virus, H1N1 Subtype Influenza A Virus, H3N2 Subtype Influenza B virus Influenza vaccines Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Male Middle Aged Tumor necrosis factor Tumor Necrosis Factor Inhibitors - therapeutic use Vaccination
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