GATA2 and PU.1 Collaborate To Activate the Expression of the Mouse Ms4a2 Gene, Encoding FcεRIβ, through Distinct Mechanisms

GATA factors GATA1 and GATA2 and ETS factor PU.1 are known to function antagonistically during hematopoietic development. In mouse mast cells, however, these factors are coexpressed and activate the expression of the Ms4a2 gene encoding the β chain of the high-affinity IgE receptor (FcεRI). The pres...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular and cellular biology 2019-11, Vol.39 (22)
Hauptverfasser:	Ohmori, Shin'ya, Ishijima, Yasushi, Numata, Suzuka, Takahashi, Mai, Sekita, Masataka, Sato, Taichi, Chugun, Keisuke, Yamamoto, Masayuki, Ohneda, Kinuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells - cytology Chromatin Immunoprecipitation DNA-Binding Proteins - metabolism GATA transcription factors GATA2 Transcription Factor - genetics GATA2 Transcription Factor - metabolism Gene Expression Regulation high-affinity IgE receptor LIM Domain Proteins - metabolism mast cell Mast Cells - metabolism Mice Mice, Knockout Promoter Regions, Genetic Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Receptors, IgE - genetics Receptors, IgE - metabolism RNA, Messenger - genetics RNA, Small Interfering - genetics Spotlight Trans-Activators - genetics Trans-Activators - metabolism transcriptional regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!