Mass Spectrometry Characterization of Thiol Conjugates Linked to Polyoxygenated Polyunsaturated Fatty Acid Species

Radical mediated oxidation of polyunsaturated fatty acids (PUFA) is known to generate a series of polyoxygenated cyclic products (PUFA-O n , n ≥ 3). Here, we describe the characterization of glutathione (GSH) conjugates bound to polyoxygenated docosahexaenoic (DHA-O n , n = 3–9), arachidonic (ARA-O...

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Veröffentlicht in:Chemical research in toxicology 2019-10, Vol.32 (10), p.2028-2041
Hauptverfasser: Chaves-Filho, Adriano B, Yoshinaga, Marcos Y, Dantas, Lucas S, Diniz, Larissa R, Pinto, Isabella F. D, Miyamoto, Sayuri
Format: Artikel
Sprache:eng
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