Strategy to prevent cardiac toxicity induced by polyacrylic acid decorated iron MRI contrast agent and investigation of its mechanism

Polyelectrolyte modified iron oxide nanoparticles have great potential applications for clinical magnetic resonance imaging (MRI) and anemia treatments, however, possible associated heart toxicity is rarely reported. Here, polyacrylic acid (PAA)-coated Fe3O4 nanoparticles (PION) were synthesized and...

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Veröffentlicht in:	Biomaterials 2019-11, Vol.222, p.119442-119442, Article 119442
Hauptverfasser:	Fu, Hao, Miao, Chongchong, Rui, Yuanpeng, Hu, Fenglin, Shen, Ming, Xu, Hong, Zhang, Chunfu, Dong, Yi, Wang, Wenping, Gu, Hongchen, Duan, Yourong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac toxicity Ion balance Iron oxide nanoparticles Polyacrylic acid
Online-Zugang:	Volltext
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