From atoms to physiology: what it takes to really understand inflammasomes

Rapid inflammatory responses to cytosolic threats are mediated by inflammasomes – large macromolecular signalling complexes that control the activation of the pro‐inflammatory cytokines interleukin (IL)‐1β and IL‐18, as well as cell death by pyroptosis. Different inflammasome sensors are activated b...

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Bibliographische Detailangaben

Veröffentlicht in:	The Journal of physiology 2019-11, Vol.597 (22), p.5335-5348
1. Verfasser:	Schmidt, Florian I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Caspase cell biology Cell death Cytokines Inflammasomes Inflammation Macromolecules Nanobodies Polymerization Pyroptosis Signal transduction single domain antibodies
Online-Zugang:	Volltext
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