Biotechnological Applications of MBD Domain Proteins for DNA Methylation Analysis

5-Methylcytosine binding domain (MBD) family proteins are essential readers of DNA methylation. Their methylation specific DNA binding has been exploited in the context of two main groups of important biotechnological applications. In the first, an MBD domain is used to bind methylated DNA in vitro....

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Veröffentlicht in:	Journal of molecular biology 2020-03, Vol.432 (6), p.1816-1823
Hauptverfasser:	Jeltsch, Albert, Broche, Julian, Lungu, Cristiana, Bashtrykov, Pavel
Format:	Artikel
Sprache:	eng
Schlagworte:	BiAD sensor DNA methylation analysis MBD imaging MBD pulldown
Online-Zugang:	Volltext
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