Mitochondrial fission protein 1 up-regulation ameliorates senescence-related endothelial dysfunction of human endothelial progenitor cells

Background We investigated the contribution of mitochondrial dysfunction to the senescence of human endothelial progenitor cells (EPCs) expanded in vitro and the underlying molecular mechanism. Methods and results Serial passage increased cell doubling time and those cells reaching the doubling time...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angiogenesis (London) 2019-11, Vol.22 (4), p.569-582
Hauptverfasser:	Wang, Hsueh-Hsiao, Wu, Yih-Jer, Tseng, Ya-Ming, Su, Cheng-Huang, Hsieh, Chin-Ling, Yeh, Hung-I
Format:	Artikel
Sprache:	eng
Schlagworte:	Bicarbonates Bioenergetics Biomedical and Life Sciences Biomedicine Cancer Research Cardiology Cell Biology Cells (biology) Fission Flow cytometry Mitochondria Morphology Oncology Ophthalmology Original Paper Oxidative stress Oxygen consumption Reactive oxygen species Senescence
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!