Prostaglandin D2 synthase modulates macrophage activity and accumulation in injured peripheral nerves

We have previously reported that prostaglandin D2 Synthase (L‐PGDS) participates in peripheral nervous system (PNS) myelination during development. We now describe the role of L‐PGDS in the resolution of PNS injury, similarly to other members of the prostaglandin synthase family, which are important...

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Veröffentlicht in:	Glia 2020-01, Vol.68 (1), p.95-110
Hauptverfasser:	Forese, Maria Grazia, Pellegatta, Marta, Canevazzi, Paolo, Gullotta, Giorgia S., Podini, Paola, Rivellini, Cristina, Previtali, Stefano C., Bacigaluppi, Marco, Quattrini, Angelo, Taveggia, Carla
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Degeneration Dorsal root ganglia Ganglia Inflammation Inflammatory response Injuries Injury analysis macrophage Macrophages Myelin Myelination Nervous system Neurodegeneration Peripheral nerves Peripheral nervous system Permeability Phagocytes Prostaglandin D2 Prostaglandin D2 synthase Prostaglandin synthase prostaglandins Regeneration Schwann cell Schwann cells SOX2 Wallerian degeneration
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