Microglia and the aging brain: are senescent microglia the key to neurodegeneration?

The single largest risk factor for etiology of neurodegenerative diseases like Alzheimer’s disease is increased age. Therefore, understanding the changes that occur as a result of aging is central to any possible prevention or cure for such conditions. Microglia, the resident brain glial population...

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Veröffentlicht in:	Journal of neurochemistry 2019-12, Vol.151 (6), p.676-688
Hauptverfasser:	Angelova, Dafina M., Brown, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Brain Disease dystrophic Etiology Iron Microglia Neurodegeneration Neurodegenerative diseases Neuronal-glial interactions Overloading Phenotypes Risk analysis Risk factors SASP
Online-Zugang:	Volltext
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