Tailoring the Saccharomyces cerevisiae endoplasmic reticulum for functional assembly of terpene synthesis pathway

The endoplasmic reticulum (ER) is a dynamic organelle that synthesizes and folds proteins. An imbalance between the ER protein synthesis load and its folding capacity triggers the unfolded protein response, thereby restoring normal ER functions via size adjustment. Inspired by such inherent genetic...

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Veröffentlicht in:	Metabolic engineering 2019-12, Vol.56, p.50-59
Hauptverfasser:	Kim, Jae-Eung, Jang, In-Seung, Son, So-Hee, Ko, Young-Joon, Cho, Byung-Kwan, Kim, Sun Chang, Lee, Ju Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Endoplasmic Reticulum - genetics Endoplasmic Reticulum - metabolism Metabolic Engineering Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Terpenes - metabolism
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