Protoberberine compounds extracted from Chelidonium majus L. as novel natural photosensitizers for cancer therapy

It has been shown that secondary metabolites occur in Chelidonium majus L. (C. majus) crude extract and milky sap (alkaloids such as berberine, coptisine, chelidonine, chelerythrine, sanguinarine, and protopine) are biologically active compounds with a wide spectrum of pharmacological functions. Ber...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2019-11, Vol.64, p.152919-152919, Article 152919
Hauptverfasser:	Warowicka, Alicja, Popenda, Łukasz, Bartkowiak, Grażyna, Musidlak, Oskar, Litowczenko-Cybulska, Jagoda, Kuźma, Dorota, Nawrot, Robert, Jurga, Stefan, Goździcka-Józefiak, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - chemistry Alkaloids - isolation & purification Alkaloids - pharmacology Anticancer properties Apoptosis Apoptosis - drug effects Berberine Alkaloids - chemistry Berberine Alkaloids - isolation & purification Berberine Alkaloids - pharmacology Cell Line, Tumor Cervical cancer Chelidonium - chemistry Chelidonium majus L Humans Photodynamic therapy Photosensitizing Agents - chemistry Photosensitizing Agents - isolation & purification Photosensitizing Agents - pharmacology Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Stems - chemistry Plants, Medicinal Protoberberine alkaloids
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