Changes in the expression levels of CB1 and GLP‐1R mRNAs and microRNAs 33a and 122 in the liver of type 2 diabetic rats treated with ghrelin

The aim of the study is to clarify the effect of ghrelin treatment on the messenger RNA (mRNA) expression of the cannabinoid receptor 1 (Cnr1/CB1) and glucagon‐like peptide 1 receptor (Glp1r/GLP‐1R) as well as microRNAs (miR)‐122 and miR‐33a in the liver of rats with type 2 diabetes mellitus (T2DM)....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biochemical and molecular toxicology 2019-10, Vol.33 (10), p.e22388-n/a
Hauptverfasser:	Coskun, Zeynep M., Beydogan, Alisa B., Bolkent, Sema
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cannabinoid CB1 receptors Cholesterol Density Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - genetics Drinking water Fructose Gene expression Ghrelin Ghrelin - administration & dosage Glucagon Glucagon-Like Peptide-1 Receptor - genetics Level (quantity) Lipids Liver Liver - metabolism microRNA MicroRNAs MicroRNAs - genetics miRNA mRNA expression Polymerase chain reaction Rats Rats, Sprague-Dawley Receptor, Cannabinoid, CB1 - genetics RNA, Messenger - genetics Rodents Streptozocin Triglycerides type 2 diabetes mellitus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!