Cadmium exposure triggers mitochondrial dysfunction and oxidative stress in chicken (Gallus gallus) kidney via mitochondrial UPR inhibition and Nrf2-mediated antioxidant defense activation

Cadmium (Cd) is a widespread environmental pollutant that accumulates in living systems and represents a significant global health hazard. Cd poses a toxicity threat to both human and animal health, including that of birds. Further knowledge of Cd toxicology pathways will allow for a better understa...

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Veröffentlicht in:	The Science of the total environment 2019-11, Vol.689, p.1160-1171
Hauptverfasser:	Ge, Jing, Zhang, Cong, Sun, Yan-Chun, Zhang, Qi, Lv, Mei-Wei, Guo, Kai, Li, Jin-Long
Format:	Artikel
Sprache:	eng
Schlagworte:	Cadmium Mitochondrial dynamic homeostasis Mitochondrial unfolded protein response Nephrotoxicity Nrf2 antioxidant defense
Online-Zugang:	Volltext
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