The alarmin S100A9 hampers osteoclast differentiation from human circulating precursors by reducing the expression of RANK

ABSTRACTThe alarmin S100A8/A9 is implicated in sterile inflammation‐induced bone resorption and has been shown to increase the bone‐resorptive capacity of mature osteoclasts. Here, we investigated the effects of S100A9 on osteoclast differentiation from human CD14+ circulating precursors. Hereto, hu...

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Veröffentlicht in:	The FASEB journal 2019-09, Vol.33 (9), p.10104-10115
Hauptverfasser:	Di Ceglie, Irene, Blom, Arjen B., Davar, Robab, Logie, Colin, Martens, Joost H. A., Habibi, Ehsan, Böttcher, Lisa‐Marie, Roth, Johannes, Vogl, Thomas, Goodyear, Carl S., Kraan, Peter M., Lent, Peter L., Bosch, Martijn H.
Format:	Artikel
Sprache:	eng
Schlagworte:	bone epigenetic regulation S100A8/A9
Online-Zugang:	Volltext
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