Beneficial effects of bardoxolone methyl, an Nrf2 activator, on crush-related acute kidney injury in rats

Purpose The purpose of this study was to investigate the effects of bardoxolone methyl (BM), a nuclear factor erythroid 2-related factor 2 (Nrf2) activator, on acute kidney injury in a rat model of crush syndrome model. Methods Sixty-four rats were separated equally into eight groups, sham (sterile...

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Veröffentlicht in:	European journal of trauma and emergency surgery (Munich : 2007) 2021-02, Vol.47 (1), p.241-250
Hauptverfasser:	Kadıoğlu, Emine, Tekşen, Yasemin, Koçak, Cengiz, Koçak, Fatma Emel
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Creatinine Critical Care Medicine Drug therapy Emergency medical care Emergency Medicine Injuries Intensive Kidneys Medicine Medicine & Public Health Original Article Rodents Sports Medicine Surgery Surgical Orthopedics Traumatic Surgery
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