Characterization of 3‑[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase

Phosphoenolpyruvate carboxykinase (PEPCK) has traditionally been characterized for its role in the first committed step of gluconeogenesis. The current understanding of PEPCK’s metabolic role has recently expanded to include it serving as a general mediator of tricarboxylic acid cycle flux. Selectiv...

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Veröffentlicht in:	Biochemistry (Easton) 2019-09, Vol.58 (37), p.3918-3926
Hauptverfasser:	Mcleod, Matthew J, Krismanich, Anthony P, Assoud, Abdeljalil, Dmitrienko, Gary I, Holyoak, Todd
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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