AOPERA: A proposed methodology and inventory of effective tools to link chemicals to adverse outcome pathways

New approaches, like the Adverse Outcome Pathway (AOP) framework, have been developed to describe how chemicals cause toxicity by linking in vitro assays to adverse health outcomes. However, approaches, tools and resources for development of AOPs have not been well described. Here we review informat...

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Veröffentlicht in:ALTEX, alternatives to animal experimentation alternatives to animal experimentation, 2020-01, Vol.37 (1), p.64-74
Hauptverfasser: Rycroft, Taylor E, Foran, Christy M, Thrash, Adam, Cegan, Jeffrey C, Zollinger, Robert, Linkov, Igor, Perkins, Edward J, Garcia-Reyero, Natàlia
Format: Artikel
Sprache:eng
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