Stem Cell Therapy: Curcumin Does the Trick
Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and m...
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Veröffentlicht in: | Phytotherapy research 2019-11, Vol.33 (11), p.2927-2937 |
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container_title | Phytotherapy research |
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creator | Sharifi, Simin Zununi Vahed, Sepideh Ahmadian, Elham Maleki Dizaj, Solmaz Abedi, Atefeh Hosseiniyan Khatibi, Seyed Mahdi Samiei, Mohammad |
description | Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin. |
doi_str_mv | 10.1002/ptr.6482 |
format | Article |
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Zununi Vahed, Sepideh ; Ahmadian, Elham ; Maleki Dizaj, Solmaz ; Abedi, Atefeh ; Hosseiniyan Khatibi, Seyed Mahdi ; Samiei, Mohammad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3492-af5e47622a3fca87db1eaf93b55cd16afe528c6741c82805ef5c4083c02099e73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Animals</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Anticancer properties</topic><topic>Antioxidants</topic><topic>Antioxidants - pharmacology</topic><topic>Biocompatibility</topic><topic>Cell differentiation</topic><topic>Cell Differentiation - drug effects</topic><topic>Cell proliferation</topic><topic>Cell Proliferation - drug effects</topic><topic>Cell- and Tissue-Based Therapy - methods</topic><topic>Curcumin</topic><topic>Curcumin - pharmacology</topic><topic>Diet</topic><topic>differentiation</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Neuroprotection</topic><topic>Regeneration</topic><topic>Regeneration - drug effects</topic><topic>stem cell</topic><topic>Stem cells</topic><topic>Stem Cells - drug effects</topic><topic>Stem Cells - physiology</topic><topic>Toxicity</topic><topic>Wound healing</topic><topic>Wound Healing - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sharifi, Simin</creatorcontrib><creatorcontrib>Zununi Vahed, Sepideh</creatorcontrib><creatorcontrib>Ahmadian, Elham</creatorcontrib><creatorcontrib>Maleki Dizaj, Solmaz</creatorcontrib><creatorcontrib>Abedi, Atefeh</creatorcontrib><creatorcontrib>Hosseiniyan Khatibi, Seyed Mahdi</creatorcontrib><creatorcontrib>Samiei, Mohammad</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Phytotherapy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sharifi, Simin</au><au>Zununi Vahed, Sepideh</au><au>Ahmadian, Elham</au><au>Maleki Dizaj, Solmaz</au><au>Abedi, Atefeh</au><au>Hosseiniyan Khatibi, Seyed Mahdi</au><au>Samiei, Mohammad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stem Cell Therapy: Curcumin Does the Trick</atitle><jtitle>Phytotherapy research</jtitle><addtitle>Phytother Res</addtitle><date>2019-11</date><risdate>2019</risdate><volume>33</volume><issue>11</issue><spage>2927</spage><epage>2937</epage><pages>2927-2937</pages><issn>0951-418X</issn><eissn>1099-1573</eissn><abstract>Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. 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subjects | Animals Anti-Inflammatory Agents - pharmacology Anticancer properties Antioxidants Antioxidants - pharmacology Biocompatibility Cell differentiation Cell Differentiation - drug effects Cell proliferation Cell Proliferation - drug effects Cell- and Tissue-Based Therapy - methods Curcumin Curcumin - pharmacology Diet differentiation Humans Inflammation Neuroprotection Regeneration Regeneration - drug effects stem cell Stem cells Stem Cells - drug effects Stem Cells - physiology Toxicity Wound healing Wound Healing - drug effects |
title | Stem Cell Therapy: Curcumin Does the Trick |
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