Stem Cell Therapy: Curcumin Does the Trick

Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Phytotherapy research 2019-11, Vol.33 (11), p.2927-2937
Hauptverfasser: Sharifi, Simin, Zununi Vahed, Sepideh, Ahmadian, Elham, Maleki Dizaj, Solmaz, Abedi, Atefeh, Hosseiniyan Khatibi, Seyed Mahdi, Samiei, Mohammad
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 2937
container_issue 11
container_start_page 2927
container_title Phytotherapy research
container_volume 33
creator Sharifi, Simin
Zununi Vahed, Sepideh
Ahmadian, Elham
Maleki Dizaj, Solmaz
Abedi, Atefeh
Hosseiniyan Khatibi, Seyed Mahdi
Samiei, Mohammad
description Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin.
doi_str_mv 10.1002/ptr.6482
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2281110595</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2281110595</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3492-af5e47622a3fca87db1eaf93b55cd16afe528c6741c82805ef5c4083c02099e73</originalsourceid><addsrcrecordid>eNp1kM1Kw0AYRQdRbK2CTyABNyKkzjc_ycSdxF8QFI3gbphOv9DUpIkzCdK3N7VVQXB1N4fD5RByCHQMlLKzpnXjSCi2RYZAkyQEGfNtMqSJhFCAeh2QPe_nlNKEUbFLBhyEZCziQ3L63GIVpFiWQTZDZ5rleZB2znZVsQgua_RBO8Mgc4V92yc7uSk9Hmx2RF6ur7L0Nrx_uLlLL-5Dy0XCQpNLFHHEmOG5NSqeTgBNnvCJlHYKkclRMmWjWIBVTFGJubSCKm4p669jzEfkZO1tXP3eoW91VXjbPzQLrDuvGVMAQGUie_T4DzqvO7fo32nGAUQUcU5_hdbV3jvMdeOKyrilBqpX_XTfT6_69ejRRthNKpz-gN_BeiBcAx9Fict_Rfoxe_oSfgKX_nY-</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2311466330</pqid></control><display><type>article</type><title>Stem Cell Therapy: Curcumin Does the Trick</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Sharifi, Simin ; Zununi Vahed, Sepideh ; Ahmadian, Elham ; Maleki Dizaj, Solmaz ; Abedi, Atefeh ; Hosseiniyan Khatibi, Seyed Mahdi ; Samiei, Mohammad</creator><creatorcontrib>Sharifi, Simin ; Zununi Vahed, Sepideh ; Ahmadian, Elham ; Maleki Dizaj, Solmaz ; Abedi, Atefeh ; Hosseiniyan Khatibi, Seyed Mahdi ; Samiei, Mohammad</creatorcontrib><description>Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin.</description><identifier>ISSN: 0951-418X</identifier><identifier>EISSN: 1099-1573</identifier><identifier>DOI: 10.1002/ptr.6482</identifier><identifier>PMID: 31452263</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Animals ; Anti-Inflammatory Agents - pharmacology ; Anticancer properties ; Antioxidants ; Antioxidants - pharmacology ; Biocompatibility ; Cell differentiation ; Cell Differentiation - drug effects ; Cell proliferation ; Cell Proliferation - drug effects ; Cell- and Tissue-Based Therapy - methods ; Curcumin ; Curcumin - pharmacology ; Diet ; differentiation ; Humans ; Inflammation ; Neuroprotection ; Regeneration ; Regeneration - drug effects ; stem cell ; Stem cells ; Stem Cells - drug effects ; Stem Cells - physiology ; Toxicity ; Wound healing ; Wound Healing - drug effects</subject><ispartof>Phytotherapy research, 2019-11, Vol.33 (11), p.2927-2937</ispartof><rights>2019 John Wiley &amp; Sons, Ltd.</rights><rights>John Wiley &amp; Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3492-af5e47622a3fca87db1eaf93b55cd16afe528c6741c82805ef5c4083c02099e73</citedby><cites>FETCH-LOGICAL-c3492-af5e47622a3fca87db1eaf93b55cd16afe528c6741c82805ef5c4083c02099e73</cites><orcidid>0000-0002-3020-3779</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fptr.6482$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fptr.6482$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31452263$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sharifi, Simin</creatorcontrib><creatorcontrib>Zununi Vahed, Sepideh</creatorcontrib><creatorcontrib>Ahmadian, Elham</creatorcontrib><creatorcontrib>Maleki Dizaj, Solmaz</creatorcontrib><creatorcontrib>Abedi, Atefeh</creatorcontrib><creatorcontrib>Hosseiniyan Khatibi, Seyed Mahdi</creatorcontrib><creatorcontrib>Samiei, Mohammad</creatorcontrib><title>Stem Cell Therapy: Curcumin Does the Trick</title><title>Phytotherapy research</title><addtitle>Phytother Res</addtitle><description>Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin.</description><subject>Animals</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>Anticancer properties</subject><subject>Antioxidants</subject><subject>Antioxidants - pharmacology</subject><subject>Biocompatibility</subject><subject>Cell differentiation</subject><subject>Cell Differentiation - drug effects</subject><subject>Cell proliferation</subject><subject>Cell Proliferation - drug effects</subject><subject>Cell- and Tissue-Based Therapy - methods</subject><subject>Curcumin</subject><subject>Curcumin - pharmacology</subject><subject>Diet</subject><subject>differentiation</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Neuroprotection</subject><subject>Regeneration</subject><subject>Regeneration - drug effects</subject><subject>stem cell</subject><subject>Stem cells</subject><subject>Stem Cells - drug effects</subject><subject>Stem Cells - physiology</subject><subject>Toxicity</subject><subject>Wound healing</subject><subject>Wound Healing - drug effects</subject><issn>0951-418X</issn><issn>1099-1573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM1Kw0AYRQdRbK2CTyABNyKkzjc_ycSdxF8QFI3gbphOv9DUpIkzCdK3N7VVQXB1N4fD5RByCHQMlLKzpnXjSCi2RYZAkyQEGfNtMqSJhFCAeh2QPe_nlNKEUbFLBhyEZCziQ3L63GIVpFiWQTZDZ5rleZB2znZVsQgua_RBO8Mgc4V92yc7uSk9Hmx2RF6ur7L0Nrx_uLlLL-5Dy0XCQpNLFHHEmOG5NSqeTgBNnvCJlHYKkclRMmWjWIBVTFGJubSCKm4p669jzEfkZO1tXP3eoW91VXjbPzQLrDuvGVMAQGUie_T4DzqvO7fo32nGAUQUcU5_hdbV3jvMdeOKyrilBqpX_XTfT6_69ejRRthNKpz-gN_BeiBcAx9Fict_Rfoxe_oSfgKX_nY-</recordid><startdate>201911</startdate><enddate>201911</enddate><creator>Sharifi, Simin</creator><creator>Zununi Vahed, Sepideh</creator><creator>Ahmadian, Elham</creator><creator>Maleki Dizaj, Solmaz</creator><creator>Abedi, Atefeh</creator><creator>Hosseiniyan Khatibi, Seyed Mahdi</creator><creator>Samiei, Mohammad</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7TK</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3020-3779</orcidid></search><sort><creationdate>201911</creationdate><title>Stem Cell Therapy: Curcumin Does the Trick</title><author>Sharifi, Simin ; Zununi Vahed, Sepideh ; Ahmadian, Elham ; Maleki Dizaj, Solmaz ; Abedi, Atefeh ; Hosseiniyan Khatibi, Seyed Mahdi ; Samiei, Mohammad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3492-af5e47622a3fca87db1eaf93b55cd16afe528c6741c82805ef5c4083c02099e73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Animals</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Anticancer properties</topic><topic>Antioxidants</topic><topic>Antioxidants - pharmacology</topic><topic>Biocompatibility</topic><topic>Cell differentiation</topic><topic>Cell Differentiation - drug effects</topic><topic>Cell proliferation</topic><topic>Cell Proliferation - drug effects</topic><topic>Cell- and Tissue-Based Therapy - methods</topic><topic>Curcumin</topic><topic>Curcumin - pharmacology</topic><topic>Diet</topic><topic>differentiation</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Neuroprotection</topic><topic>Regeneration</topic><topic>Regeneration - drug effects</topic><topic>stem cell</topic><topic>Stem cells</topic><topic>Stem Cells - drug effects</topic><topic>Stem Cells - physiology</topic><topic>Toxicity</topic><topic>Wound healing</topic><topic>Wound Healing - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sharifi, Simin</creatorcontrib><creatorcontrib>Zununi Vahed, Sepideh</creatorcontrib><creatorcontrib>Ahmadian, Elham</creatorcontrib><creatorcontrib>Maleki Dizaj, Solmaz</creatorcontrib><creatorcontrib>Abedi, Atefeh</creatorcontrib><creatorcontrib>Hosseiniyan Khatibi, Seyed Mahdi</creatorcontrib><creatorcontrib>Samiei, Mohammad</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Phytotherapy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sharifi, Simin</au><au>Zununi Vahed, Sepideh</au><au>Ahmadian, Elham</au><au>Maleki Dizaj, Solmaz</au><au>Abedi, Atefeh</au><au>Hosseiniyan Khatibi, Seyed Mahdi</au><au>Samiei, Mohammad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stem Cell Therapy: Curcumin Does the Trick</atitle><jtitle>Phytotherapy research</jtitle><addtitle>Phytother Res</addtitle><date>2019-11</date><risdate>2019</risdate><volume>33</volume><issue>11</issue><spage>2927</spage><epage>2937</epage><pages>2927-2937</pages><issn>0951-418X</issn><eissn>1099-1573</eissn><abstract>Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti‐inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>31452263</pmid><doi>10.1002/ptr.6482</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-3020-3779</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0951-418X
ispartof Phytotherapy research, 2019-11, Vol.33 (11), p.2927-2937
issn 0951-418X
1099-1573
language eng
recordid cdi_proquest_miscellaneous_2281110595
source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Animals
Anti-Inflammatory Agents - pharmacology
Anticancer properties
Antioxidants
Antioxidants - pharmacology
Biocompatibility
Cell differentiation
Cell Differentiation - drug effects
Cell proliferation
Cell Proliferation - drug effects
Cell- and Tissue-Based Therapy - methods
Curcumin
Curcumin - pharmacology
Diet
differentiation
Humans
Inflammation
Neuroprotection
Regeneration
Regeneration - drug effects
stem cell
Stem cells
Stem Cells - drug effects
Stem Cells - physiology
Toxicity
Wound healing
Wound Healing - drug effects
title Stem Cell Therapy: Curcumin Does the Trick
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T20%3A33%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Stem%20Cell%20Therapy:%20Curcumin%20Does%20the%20Trick&rft.jtitle=Phytotherapy%20research&rft.au=Sharifi,%20Simin&rft.date=2019-11&rft.volume=33&rft.issue=11&rft.spage=2927&rft.epage=2937&rft.pages=2927-2937&rft.issn=0951-418X&rft.eissn=1099-1573&rft_id=info:doi/10.1002/ptr.6482&rft_dat=%3Cproquest_cross%3E2281110595%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2311466330&rft_id=info:pmid/31452263&rfr_iscdi=true