Serotonergic influence on depressive symptoms and trait anxiety is mediated by negative life events and frontal activation in children and adolescents

Depression and anxiety are common in childhood and adolescence. Even though cardinal symptoms differ, there is a considerable overlap regarding the pathogenic influence of serotonergic innervation, negative life experience, disturbed emotion perception/affect regulation, and impaired neural function...

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Veröffentlicht in:	European child & adolescent psychiatry 2020-05, Vol.29 (5), p.691-706
Hauptverfasser:	Kneer, Katharina, Reinhard, Julia, Ziegler, Christiane, Slyschak, Anna, Schiele, Miriam, Vietz, Melanie, Peters, Katharina, Meisenzahl, Eva M., Pauli, Paul, Reif, Andreas, Deckert, Jürgen, Romanos, Marcel, Domschke, Katharina, Neufang, Susanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Anxiety Brain Brain mapping Child & adolescent psychiatry Child and Adolescent Psychiatry Childhood Children Emotional regulation Frontal gyrus Functional magnetic resonance imaging Genotype & phenotype Genotypes Innervation Medicine Medicine & Public Health Mental depression Negative events Negative life events Original Contribution Phenotypes Psychiatry Trait anxiety
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