In‐vitro cytotoxicity of various Siphonochilus aethiopicus (Schweinf.) B.L. Burtt extracts in combination with selected tableting excipients

Objectives To investigate the cytotoxic potential of S. aethiopicus extracts in combination with chitosan and Pharmacel®101, on two cell lines. Methods Extracts were chemically characterised utilising UPLC‐Q‐TOF/MS, followed by determination of cell viability and membrane integrity. Key findings Eth...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2019-11, Vol.71 (11), p.1714-1724
Hauptverfasser:	Erasmus, Mandi, Plessis, Lissinda H., Viljoen, Joe M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Apoptosis - drug effects Caco-2 Cells Cell death Cell Line, Tumor Cell lines Cell Survival - drug effects Cell viability Chitosan crude extracts Cytotoxicity Diet Diethyl ether Ethanol Excipients Excipients - chemistry Exposure Hep G2 Cells Humans Plant Extracts - pharmacology Siphonochilus aethiopicus tablet excipients Tablets - chemistry Tablets - pharmacology Zingiberaceae - chemistry
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