Notch signaling is involved in Fgf23 upregulation in osteocytes

Fgf23 acts as a phosphaturic factor secreted from osteocytes in bone, but the mechanism regulating Fgf23 is not fully understood. Here, we showed the colocalization of Fgf23, Notch, and Hes1, a downstream target of Notch signaling, in numerous osteocytes in cortical bone of femur in wild-type mice....

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-10, Vol.518 (2), p.233-238
Hauptverfasser:	Tamamura, Yoshihiro, Sakamoto, Kei, Katsube, Ken-ichi, Yamaguchi, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone FGF23 Notch Osteocyte Transgenic mouse
Online-Zugang:	Volltext
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