Effects of Dipeptidyl Peptidase-4 Inhibitor Linagliptin on Left Ventricular Dysfunction in Patients with Type 2 Diabetes and Concentric Left Ventricular Geometry (the DYDA 2™ Trial). Rationale, Design, and Baseline Characteristics of the Study Population

Purpose A multicentre, randomized, double-blind, placebo-controlled, parallel-group study aimed to define the potential positive effect of dipeptidyl peptidase-4 inhibition on left ventricular systolic function (LVSF) beyond glycemic control in type 2 diabetes mellitus (T2DM) (DYDA 2™ trial). Method...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiovascular drugs and therapy 2019-10, Vol.33 (5), p.547-555
Hauptverfasser:	Giorda, Carlo Bruno, Cioffi, Giovanni, Lucci, Donata, Nada, Elisa, Ognibeni, Federica, Mancusi, Costantino, Latini, Roberto, Maggioni, Aldo P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers - blood Blood Glucose - drug effects Blood Glucose - metabolism Cardiology Clinical trials Control methods Coronary artery disease Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - drug therapy Dipeptidyl-peptidase IV Dipeptidyl-Peptidase IV Inhibitors - adverse effects Dipeptidyl-Peptidase IV Inhibitors - therapeutic use Double-Blind Method Dyslipidemia Echocardiography Female Glycated Hemoglobin A - metabolism Heart diseases Humans Hypertension Inhibitors Insulin Italy Linagliptin - adverse effects Linagliptin - therapeutic use Longitude Male Males Medicine Medicine & Public Health Middle Aged Multicenter Studies as Topic Original Article Peptidase Population studies Randomization Randomized Controlled Trials as Topic Signs and symptoms Time Factors Treatment Outcome Ventricle Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - drug therapy Ventricular Dysfunction, Left - physiopathology Ventricular Function, Left - drug effects Ventricular Remodeling - drug effects Wall thickness
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!