Gastric environment-stable oral nanocarriers for in situ colorectal cancer therapy

Colorectal cancer (CRC) is a prevalent and fatal cancer. Oral administration provided the potential for in situ treatment of the colorectal cancer. However, drugs couldn't be well-absorbed mainly due to its degradation in the gastric area and poor intestinal permeability. In this study, we synt...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of biological macromolecules 2019-10, Vol.139, p.1035-1045
Hauptverfasser:	Wang, Ting, Wang, Fangqin, Sun, Mengjie, Tian, Meiping, Mu, Yuzhi, Chen, Xiguang, Liu, Ya
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adsorption Caco-2 Cells Chitosan - analogs & derivatives Chitosan - chemistry Colorectal cancer Colorectal Neoplasms - drug therapy Curcumin - administration & dosage Curcumin - chemistry Curcumin - therapeutic use Deoxycholic Acid - chemistry Drug Carriers - chemistry Drug Carriers - metabolism Drug Carriers - toxicity Drug Liberation Drug Stability Gastric environment Gastric Mucosa - metabolism Hemolysis - drug effects Humans Intestinal Absorption Materials Testing Nanocarriers Nanoparticles - chemistry Oral delivery Stable Temperature
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!