Recent nanotechnological interventions targeting PI3K/Akt/mTOR pathway: A focus on breast cancer

Breast cancer is the major cause of deaths in women worldwide. Detection and treatment of breast cancer at earlier stages of the disease has shown encouraging results. Modern genomic technologies facilitated several therapeutic options however the diagnosis of the disease at an advanced stage claim...

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Veröffentlicht in:	Seminars in cancer biology 2019-12, Vol.59, p.133-146
Hauptverfasser:	Sharma, VarRuchi, Sharma, Anil K., Punj, Vasu, Priya, Panneerselvam
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor Breast cancer Breast cancer biomarkers Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - pathology Deregulated genes Female Humans Molecular Targeted Therapy Nanotechnological interventions Nanotechnology Phosphatidylinositol 3-Kinases - metabolism PI3K/Akt/mTOR pathway Protein Kinase Inhibitors - chemistry Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Proto-Oncogene Proteins c-akt - metabolism Signal Transduction - drug effects Theranostic Nanomedicine TOR Serine-Threonine Kinases - metabolism Translational Medical Research
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