LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro

BACKGROUND: Increasing evidence shows that long non-coding RNAs (lncRNAs) play a key role in the development of various cancers. Zinc finger antisense 1 (ZFAS1) is a novel lncRNA with previously demonstrated associations with several types of cancer. Here we examined the expression and potential fun...

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Veröffentlicht in:	Cancer biomarkers : section A of Disease markers 2019-01, Vol.26 (2), p.171-182
Hauptverfasser:	Wang, Xiaoqiong, Jin, Qiaozhi, Wang, Xue, Chen, Wubing, Cai, Zhiyi
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Antisense RNA Apoptosis Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Biotechnology Cancer Cell Cycle Cell growth Cell Movement Cell Proliferation Gene Expression Regulation, Neoplastic Humans In Vitro Techniques Kinases Mesenchyme Nasopharyngeal carcinoma Nasopharyngeal Carcinoma - genetics Nasopharyngeal Carcinoma - metabolism Nasopharyngeal Carcinoma - pathology Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - metabolism Nasopharyngeal Neoplasms - pathology Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Prognosis Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism RNA, Long Noncoding - genetics Signal transduction Signaling siRNA Throat cancer Tumor Cells, Cultured Zinc finger proteins
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