TMPRSS3 regulates cell viability and apoptosis processes of HEI‐OC1 cells via regulation of the circ‐Slc4a2, miR‐182 and Akt cascade

Background The present study aimed to investigate the functions and regulation mechanism of the transmembrane protease, serine 3 (TMPRSS3), which plays an important role in sensorineural hearing loss. Methods House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, comprising auditory‐related cells, we...

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Veröffentlicht in:	The journal of gene medicine 2019-10, Vol.21 (10), p.e3118-n/a
Hauptverfasser:	Zhang, Zhi‐Wen, Pang, Bo, Chen, Yi‐Chao, Peng, An‐Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Apoptosis Cell viability Circular RNA Gene therapy Genomes Hearing loss Organ of Corti Polymerase chain reaction Primers RAS signaling pathway Ribonucleic acid RNA sensorineural hearing loss Serine Signal transduction TMPRSS3
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