Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer

[Display omitted] Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers. Our previous studies have proven that Trillium tschonoskii Maxim. (TTM), a traditional Chinese medicine, possesses potent anti-tumor effect. However, the detailed components and molecular mechani...

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Veröffentlicht in:	Pharmacological research 2019-09, Vol.147, p.104396-104396, Article 104396
Hauptverfasser:	Teng, Jin-Feng, Qin, Da-Lian, Mei, Qi-Bing, Qiu, Wen-Qiao, Pan, Rong, Xiong, Rui, Zhao, Ya, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Tang, Yong, Yu, Chong-Lin, Zhang, Feng, Wu, Jian-Ming, Wu, An-Guo
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autophagy mTOR Polyphyllin VI ROS
Online-Zugang:	Volltext
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