Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length

A newborn's birth weight for gestational age provides important insights into his or her fetal growth and well-being. While the underlying mechanisms regulating fetal growth remain to be fully elucidated, the IGF axis plays an important role. Some components of this axis have been well-characte...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2019-11, Vol.100, p.153959-153959, Article 153959
Hauptverfasser:	DiPrisco, Bridget, Kumar, Ajay, Kalra, Bhanu, Savjani, Gopal V., Michael, Zoe, Farr, Olivia, Papathanasiou, Aimilia Eirini, Christou, Helen, Mantzoros, Christos
Format:	Artikel
Sprache:	eng
Schlagworte:	Case-Control Studies Cord blood Female Fetal growth Humans IGF axis IGF binding proteins Infant, Newborn Insulin-Like Growth Factor Binding Protein 4 - metabolism Insulin-Like Growth Factor Binding Protein 5 - metabolism Insulin-Like Growth Factor I - metabolism Insulin-Like Growth Factor II - metabolism Isoenzymes - chemistry Isoenzymes - metabolism Placenta - enzymology Placental proteases Pregnancy Pregnancy-Associated Plasma Protein-A - chemistry Pregnancy-Associated Plasma Protein-A - metabolism Protein Binding Proteolysis
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