Aspergillus specific nested PCR from the site of infection is superior to testing concurrent blood samples in immunocompromised patients with suspected invasive aspergillosis

Summary Invasive aspergillosis (IA) is a severe complication in immunocompromised patients. Early diagnosis is crucial to decrease its high mortality, yet the diagnostic gold standard (histopathology and culture) is time‐consuming and cannot offer early confirmation of IA. Detection of IA by polymer...

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Veröffentlicht in:	Mycoses 2019-11, Vol.62 (11), p.1035-1042
Hauptverfasser:	Boch, Tobias, Spiess, Birgit, Heinz, Werner, Cornely, Oliver A., Schwerdtfeger, Rainer, Hahn, Joachim, Krause, Stefan W., Duerken, Matthias, Bertz, Hartmut, Reuter, Stefan, Kiehl, Michael, Claus, Bernd, Deckert, Peter Markus, Hofmann, Wolf‐Karsten, Buchheidt, Dieter, Reinwald, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged antifungal Aspergillosis Aspergillosis - blood Aspergillosis - diagnosis Aspergillosis - microbiology Aspergillus Aspergillus - isolation & purification BAL blood cerebrospinal fluid Child Child, Preschool comparison Diagnosis Female Humans Immunocompromised Host Immunocompromised hosts Infections Invasive Fungal Infections - blood Invasive Fungal Infections - diagnosis Invasive Fungal Infections - microbiology Invasiveness Male Middle Aged Molecular Diagnostic Techniques - methods Molecular Diagnostic Techniques - standards Patients PCR Polymerase chain reaction Polymerase Chain Reaction - standards Prophylaxis Retrospective Studies Sensitivity and Specificity Young Adult
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