Diagnostic DNA Methylation Biomarkers for Renal Cell Carcinoma: A Systematic Review

The 5-yr survival of early-stage renal cell carcinoma (RCC) is approximately 93%, but once metastasised, the 5-yr survival plummets to 12%, indicating that early RCC detection is crucial to improvement in survival. DNA methylation biomarkers have been suggested to be of potential diagnostic value; h...

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Veröffentlicht in:	European urology oncology 2021-04, Vol.4 (2), p.215-226
Hauptverfasser:	Lommen, Kim, Vaes, Nathalie, Aarts, Maureen J., van Roermund, Joep G., Schouten, Leo J., Oosterwijk, Egbert, Melotte, Veerle, Tjan-Heijnen, Vivianne C., van Engeland, Manon, Smits, Kim M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Carcinoma, Renal Cell - diagnosis Carcinoma, Renal Cell - genetics Diagnosis Diagnostic Tests, Routine DNA Methylation Humans Kidney cancer Kidney Neoplasms - diagnosis Kidney Neoplasms - genetics Promoter CpG island methylation Renal cell carcinoma Reproducibility of Results
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