On the immunoregulatory role of statins in multiple sclerosis: the effects on Th17 cells

Statins, the cholesterol-lowering drugs, also possess immunomodulatory properties, affecting among others T cell activation and differentiation, antigen presentation, and regulatory T cell (Tregs) maintenance and differentiation. Their effects on autoagression have led investigators to assess their...

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Veröffentlicht in:	Immunologic research 2019-10, Vol.67 (4-5), p.310-324
Hauptverfasser:	Ntolkeras, Georgios, Barba, Chrysanthi, Mavropoulos, Athanasios, Vasileiadis, Georgios K., Dardiotis, Efthymios, Sakkas, Lazaros I., Hadjigeorgiou, Georgios, Bogdanos, Dimitrios P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergology Animals Antigen presentation Antigens Autoimmune diseases Biomedical and Life Sciences Biomedicine Cell activation Cell differentiation Cholesterol Demyelinating diseases Demyelination Differentiation Disease Models, Animal Helper cells Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Immunologic Factors - therapeutic use Immunology Immunomodulation Immunoregulation Internal Medicine Lymphocytes Lymphocytes T Medicine/Public Health Multiple sclerosis Multiple Sclerosis - drug therapy Multiple Sclerosis - immunology Multiple Sclerosis - pathology Review Statins Th17 Cells - immunology Th17 Cells - pathology
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