Efficacy of novel recombinant fowlpox vaccine against recent Mexican H7N3 highly pathogenic avian influenza virus

•rFPV-H7/3002 vaccine protected chickens against challenge Mexican 2015 H7N3 HPAIV.•rFPV-H7/2155 vaccine protects against the 2012 outbreak virus but not 2015 H7N3 HPAIV.•2015 Mexican H7N3 HPAIV have gained additional N-glycosylation sites on the HA.•The importance of updating vaccines for long-term...

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Veröffentlicht in:	Vaccine 2019-04, Vol.37 (16), p.2232-2243
Hauptverfasser:	Criado, Miria Ferreira, Bertran, Kateri, Lee, Dong-Hun, Killmaster, Lindsay, Stephens, Christopher B., Spackman, Erica, Sa e Silva, Mariana, Atkins, Emily, Mebatsion, Teshome, Widener, Justin, Pritchard, Nikki, King, Hallie, Swayne, David E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal welfare Antibodies Antigenic drift antigenic variation Antigens Avian flu avian influenza Birds blood serum Chickens Effectiveness Epidemics fowl pox Fowlpox Fowlpox virus gastrointestinal system genes Glycosylation H7N3 hemagglutination Hemagglutination inhibition Hemagglutinins High pathogenicity avian influenza Homology Immunity Influenza Influenza A virus Mexico Morbidity mortality Mutation neutralizing antibodies Outbreaks Poultry Recombinant fowlpox virus vaccine Seeds Strains (organisms) Vaccine Vaccines viral antigens Viruses
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