Increased Bone Marrow-Specific Adipogenesis by Clofazimine Causes Impaired Fracture Healing, Osteopenia, and Osteonecrosis Without Extraskeletal Effects in Rats

Mycobacterium leprae infection causes bone lesions and osteoporosis, however, the effect of antileprosy drugs on the bone is unknown. We, therefore, set out to address it by investigating osteogenic differentiation from bone marrow (BM)-derived mesenchymal stem cells (MSCs). Out of 7 antileprosy dru...

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Veröffentlicht in:	Toxicological sciences 2019-11, Vol.172 (1), p.167-180
Hauptverfasser:	Porwal, Konica, Pal, Subhashis, Tewari, Deepshikha, Pal China, Shyamsundar, Singh, Priya, Chandra Tewari, Mahesh, Prajapati, Gurudayal, Singh, Pragati, Cheruvu, Srikanth, Khan, Yasir A, Sanyal, Sabyasachi, Gayen, Jiaur R, Ampapathi, Ravishankar, Mridha, Asit R, Chattopadhyay, Naibedya
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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