TGF-β signaling in cell fate control and cancer

Members of the transforming growth factor-β (TGF-β) family regulate cell fate decisions during early embryonic development and tissue homeostasis in the adult. Deregulation of TGF-β family signaling contributes to developmental anomalies, fibrotic disorders, tumorigenesis and immune diseases. TGF-β...

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Veröffentlicht in:	Current opinion in cell biology 2019-12, Vol.61, p.56-63
Hauptverfasser:	Yu, Yi, Feng, Xin-Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Lineage - physiology Humans Neoplasms - pathology Signal Transduction - physiology Smad Proteins - metabolism Transforming Growth Factor beta - metabolism
Online-Zugang:	Volltext
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